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Clinical questions


If the depression score is only slightly out of range—for example, 11 or 12—should I still treat for depression?

 
What is the best way to talk to a patient about a mental health diagnosis?

 
How often should I re-administer the QPD Panel?

 
A lot of my patients get multiple diagnoses on the QPD Panel. Is this common?

 
How do I know when to diagnose Somatization Disorder?

 
I am a primary care physician. Once I identify a patient as depressed, what treatment should I offer?

 
Are the results valid if a patient lies when taking the QPD Panel?

 
 
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If the depression score is only slightly out of range—for example, 11 or 12—should I still treat for depression?
Any score outside the normal reference range indicates clinically significant distress, whether or not the patient meets strict DSM-IV criteria for major depression or dysthymic disorder. A Depression score of 11 or 12 indicates a relatively mild depressive disorder. It would be appropriate to discuss the findings with the patient and review treatment options (e.g., lifestyle changes, psychotherapy). At the very least, the patient should be monitored and re-assessed periodically.

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What is the best way to talk to a patient about a mental health diagnosis?
Present the QPD Panel findings matter-of-factly, as you would any other medical finding. For example, you could simply say “Your test results show that you are suffering from depression. The symptoms you are having are part of depression, and they should clear up when you get treatment.” Here you might review the specific symptoms listed on the QPD Panel report, emphasizing that they are components of the same disorder. Many patients do not know, for example, that symptoms like fatigue, or appetite loss, or insomnia are related to depression.

Most patients are relieved and grateful when their physician addresses mental health problems, and appreciate the fact that the physician is concerned enough to do so. Patients who might otherwise deny emotional problems tend to be more open to treatment when presented with the objective QPD Panel report. Many physicians find it helpful to show the patient the report while reviewing the findings.

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How often should I re-administer the QPD Panel?
You can re-administer the test as often as desired. Patients with no known psychiatric history should be screened at least once per year as part of an annual check up. You can think of it as checking the patient’s “emotional vital signs.” For patients with mental health problems, the test should be administered more often. For example, the QPD Panel should be re-administered 4 to 6 weeks after starting a patient on an antidepressant to assess response to treatment. The patient should continue to be assessed every few months until the symptoms have remitted and the depression score is within the normal range (0 to 10). Depressed patients may not initiate follow-up appointments, so it is important to schedule appointment in advance. It is also common for depressed patients to stop taking antidepressants before the medication has time to take effect. Scheduled follow-up appointments encourage compliance and lead to better outcomes.

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A lot of my patients get multiple diagnoses on the QPD Panel. Is this common?
Comorbidity of psychiatric disorders is very high, and it is common for patients to receive more than one diagnosis. The comorbidity of depression and anxiety is so high that DSM task forces are considering a single combined diagnosis. Mood disorders are often comorbid with substance abuse, and patients with mood disorders often use alcohol or drugs in a misguided effort to self-medicate.

It is important to consider the spectrum of disorders when planning treatment. For example, a depressed patient who is abusing alcohol is unlikely to derive much benefit from treatment unless substance abuse is addressed as well. Patients with depression and panic attacks are likely to benefit from psychotherapy in addition to medication. As the number of QPD Panel diagnoses increases, the likelihood that the patient is suffering from a long-standing personality disorder (Axis II) increases as well, and the physician should be alert to this possibility. Patients with personality disorders should generally be referred to a mental health professional for treatment.

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How do I know when to diagnose Somatization Disorder?
Somatization Disorder is diagnosed only after the physician has rule out medical conditions that may be causing the symptoms. An out-of-range Somatization score simply means that the patient has reported multiple somatic symptoms that are unlikely to result from any single medical condition, which may be somatic equivalents of depression or anxiety. The score should raise the physician's index of suspicion regarding Somatization Disorder, but a thorough medical work up is indicated.

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I am a primary care physician. Once I identify a patient as depressed, what treatment should I offer?
The first intervention is to inform the patient of the QPD Panel findings. Patients are generally reassured to know that their symptoms have an explanation and treatment is available. Sometimes this alone brings about some improvement, because it offers hope to a person who may otherwise be feeling confused and hopeless.

Early treatment is advisable. Untreated depression tends to be cyclical, with depressive episodes becoming more severe over time. Psychotherapy and antidepressant medication are both effective treatments, and the patient’s preference should be a determining factor. In one study, primary care patients identified as depressed by the QPD Panel were offered the option of psychotherapy, a trial on an antidepressant, or both. The patients made good decisions and showed significant improvement at 12 week follow up, with QPD Panel depression scores decreasing an average of 7.1 points.

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Are the results valid if a patient lies when taking the QPD Panel?
The results are not valid if a patient does not answer honestly. The QPD Panel is designed for use in healthcare settings where patients voluntarily seek help. The test is an extension of the patient’s communication with his doctor, so patients generally respond candidly.

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